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Dopamine
 

offline umbroman3 from United Kingdom on 2023-01-17 14:47 [#02624280]
Points: 5900 Status: Regular



What is it


 

offline Tony Danza from nuked west on 2023-01-17 14:48 [#02624281]
Points: 3128 Status: Regular



they call it The Shitposter's Treat


 

offline recycle from Where is Phobiazero (Lincoln) (United States) on 2023-01-17 16:05 [#02624282]
Points: 38535 Status: Regular



I’m on it now


 

offline umbroman3 from United Kingdom on 2023-01-17 17:40 [#02624286]
Points: 5900 Status: Regular



dopamine imbalance can cause you to hear voices in the mind

also the messiah can communicate via telepathy and torture
people through the mental health system

also there are universities working on silent communication
between minds

what would happen if you had all three at the same time?
dopamine imbalance: schizophrenia, the messiah's telepathy:
divine punishment, silent communication: government
tyranny.

d'oh


 

offline recycle from Where is Phobiazero (Lincoln) (United States) on 2023-01-17 23:01 [#02624290]
Points: 38535 Status: Regular



d’oh is right mate


 

offline EpicMegatrax from Greatest Hits on 2023-01-17 23:48 [#02624292]
Points: 20627 Status: Addict



dopamine is "woo yeah! let's go DO IT"

serotonin is "fuck yeah i'm satisfied with that"

norepinephrine is someone stabbing you in the ass
with a pin

oxytocin is mdma. or something. i've tried a lot but
i never touched mdma because... the sources mostly garbage.
that i can say i've never touched it because the one time i
bought a tab against my better judgement it did fuckall;
could have been a carefully sculpted sweet-tart. then: that
was lucky in a way; it could have been ephedrine, dxm, and
strychnine instead of fuckall. but in any case, i feel like
there's a better way to summarize the feeling but i can't
quite find it, feeling around in the dark for it

i've never considered trying to identify cortisol. that
sounds interesting


 

offline EpicMegatrax from Greatest Hits on 2023-01-17 23:50 [#02624293]
Points: 20627 Status: Addict



we are all on all of these substances. except for those of
us who are tacitly a forgotten bit of AI software from 1997


 

offline EpicMegatrax from Greatest Hits on 2023-01-17 23:58 [#02624294]
Points: 20627 Status: Addict



i don't usually think, "oh, that'd be a good short story."
because i don't generally write them. but, hmm. someone
writes a bot in 1997; forgets about it. it keeps going for
almost 30 years. posting on the board and accumulating data.
simply being present for long enough that no one thinks to
question anymore; treated as real. that the people who have
"smart dogs" that really seem to understand english, are the
ones that speak to their dogs as if they were people. left
to its own devices, treated as real, it starts to become a
cunning troll. everything blows up when it finally figures
out how to SWAT someone. the cops go looking for the person
paying the bills for the bot, presuming it was his
deliberate act, but he's been "incommunicado" off sailing a
yacht around various DMZs or something and then the rest of
it is the chaotic fight over... well it's your bot, it had
to be deliberate?

sort of like any number of stories about a childhood toy
with [imaginary?] powers coming back to haunt your adult
life with a schema out of time. i do believe someone on the
board blew me away by referencing "drop dead fred," a movie
i saw 3/4 once, by accident, on tv, 20 years ago


 

offline Wolfslice from Bay Area, CA (United States) on 2023-01-18 06:41 [#02624295]
Points: 4065 Status: Addict | Followup to umbroman3: #02624286



>>>>what would happen if you had all three at the same
time?
dopamine imbalance: schizophrenia, the messiah's telepathy:
divine punishment, silent communication: government
tyranny.

It wouldn't be so bad, as the dopamine imbalance and
messiah's telepathy would both likely be a result of the
schizophrenia, treated with antipsychotics. A large % of
schizophrenics would have all 3 at the same time.


 

offline Wolfslice from Bay Area, CA (United States) on 2023-01-18 06:50 [#02624296]
Points: 4065 Status: Addict | Followup to EpicMegatrax: #02624292



cleaning up epic's rundown

dopamine: more like fuck yeah, let's do it AGAIN. and AGAIN.
chemical reward leading to repetitive behavior patterns.

serotonin: I'm satisfied with how I "feel." It's chemical
well being. MDMA belongs here, not with oxytocin, as it
completely floods you with it.

norepinephrine: my body is regulating it's muscular systems
correctly.

oxytocin: not even a neurotransmitter. A hormone, found in
high quantities with new parents/parental bonding/other love
based situations. If you're gonna put in oxytocin, it's
hippy-dippy to mention it but not mention-

cortisol: stress hormone (among more basic body regulatory
effects). In higher levels in people than ever because of
the near constant stressors provided by society. Lower
levels as we evolved in the African savannah.



 

offline Wolfslice from Bay Area, CA (United States) on 2023-01-18 07:05 [#02624297]
Points: 4065 Status: Addict | Followup to Wolfslice: #02624296



oh you did mention cortisol, albeit as a footnote. Sorries I
was only lookin a BULLET POINTS, probably because they lead
to a slightly dopaminergic response. You should use them
more often!


 

offline mermaidman on 2023-01-18 08:24 [#02624298]
Points: 7660 Status: Regular



i’m taking stilizan at lower doses my doctor prescribed me
not for schizophrenia though no messiah radio silence


 

offline mermaidman on 2023-01-18 08:26 [#02624299]
Points: 7660 Status: Regular



this messiah guy targets dopamine imbalance? what an asshole


 

offline EpicMegatrax from Greatest Hits on 2023-01-18 09:00 [#02624310]
Points: 20627 Status: Addict | Followup to Wolfslice: #02624296



> oxytocin: not even a neurotransmitter.

hey, yo. no one specified it had to be anywhere. i just
listed it because it is very much a distinct thing i can
identify clearly from all the rest of the mind/body noise...
that, when it hits me; i'm not wondering if i'm really sure
about it. i am sure


 

offline Wolfslice from Bay Area, CA (United States) on 2023-01-19 07:20 [#02624331]
Points: 4065 Status: Addict | Followup to EpicMegatrax: #02624310



Yeah just from what I remember in biopsychology, oxytocin
was mainly found and studied in parents and bonding with
children (particularly: animal bonding with their
offspring).

But make no mistake, MDMA is all about the serotonin. I
didn't care much for MDMA either, made me TOO open, TOO
empathetic. I took it a few times on higher doses and said
"never again." I remember that I wrote this friend a long
email about autechre's Lentic Catahcresis and it was fucking
*cringe* to read the next day.

And for the record, psilocybin and lsd ALSO block serotonin
reuptake and generally fuck with that particular
neurotransmitter. I can feel that high most on mushrooms.

Oxytocin, while mainly studied for emotional bonding, is
probably a factor in romantic love and sexual activity too,
but I definitely learned that ALL of those neurotransmitters
with proper reuptake are. To have a proper ejaculation,
iirc, you need proper reuptake of both serotonin and
dopamine, for instance. It's why most of the drugs that
inhibit uptake also cause problems with sexual function.


 

offline umbroman3 from United Kingdom on 2023-01-19 21:17 [#02624362]
Points: 5900 Status: Regular



rare xltronic thread that stayed on topic for at least 15
posts


 

offline RussellDust on 2023-01-20 11:20 [#02624380]
Points: 15617 Status: Regular



Cats


 

offline umbroman3 from United Kingdom on 2023-01-20 11:28 [#02624383]
Points: 5900 Status: Regular



meow


 

offline EpicMegatrax from Greatest Hits on 2023-01-20 23:19 [#02624389]
Points: 20627 Status: Addict | Followup to Wolfslice: #02624296



> oxytocin: not even a neurotransmitter. A hormone,
found in high quantities with new parents/parental
bonding/other love based situations. If you're gonna put in
oxytocin, it's hippy-dippy to mention it but not
mention-


alright. i would describe it as an incredibly deep feeling
of fondness. chakras are almost as bad as galen's humours,
but definite heart chakra zone. i've never messed around
with anti-anxiety drugs, benzos, etc. but it's not just
fondness, it's a feeling of just being so. completely.
comfortable. and i suspect benzos would have a lot in
common.

my point was, i recognize it very crisply and immediately.
you can actually get transdermal oxytocin patches -- i've
always wanted to get ahold of a few simply to be like...
okay, yes, this is exactly what i thought

growing up, there was one of these well-raised, hyper-social
people... and, well, i was sort of an aloof nerd (can you
imagine?) back in high school and college, and the guy made
an effort, more than anyone usually put into me, to be
friends, to come over sometime. because that's how he was
raised. to me, it felt a bit odd, but in a nice way, so
sure, come on over. then i don't know him very well and
somehow... guy would just get it out of me. boom, oxytocin
release. something in his attitude; demeanor. i have always
been incredibly envious of this. i guarantee you guy can
just turn it on in all sorts of people, and i still can't
fathom how he did it.

cortisol: afaik it doesn't have a singular drop like
oxytocin, making it harder to identify. but i have some
strong hunches


 

offline EpicMegatrax from Greatest Hits on 2023-01-20 23:51 [#02624390]
Points: 20627 Status: Addict



that yeah, i'm like 18 and he's over and i already knew what
oxytocin was and what it felt like when it dropped. really
only ever felt it with family. then right there in the
moment: he just got an oxytocin release out of me, how the
hell does he do that?

it's probably something like: he makes time to seriously
consider how to cherish someone, no matter who they are. a
view that everyone is wonderful, you just have to dig and
find it.... and, for the same reason, you can't leave anyone
behind.

so i suspect the secret was... corny as this sounds...
genuinely striving to love everyone, no matter who they are


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 00:26 [#02624391]
Points: 20627 Status: Addict



his parents both doctors, i think family money on both sides
too, kind of like "it's just a mercedes" level rich. but his
mum is a family doctor and i never heard a word about god
from any of them, but i suspect religion (jewish) was
strongly there. so he'd have a nicer car than anyone else,
but utterly not spoiled. like i described. then he got into
DJing and i think by the time he pulled the whammy on me...
yeah, i think he'd tried E and that only reinforced the
(actually properly done for once) religious upbringing


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 00:40 [#02624392]
Points: 20627 Status: Addict



they've done studies showing that, when chatting, two
peoples' brainwaves will begin to synchronize. we have
phrases for this, like, "oh, we were very much on the same
wavelength." deeper levels of this, like... when
you're spooning with someone in bed and you kind of feel
your limbs merge, like, is that my leg or yours?

the "brainwaves synchronize when people talk face to face
and feel engaged" thing has been verified by Science with
Experimental Data and all that. so it clearly does happen
between one person and another.

i've always thought: if you could somehow do brainscans on
everyone at a rave, you'd find that the brainwaves of
everyone in the whole place began to synchronize. this
explains both the feeling of collective unity, and contact
high

but it's kind of hard to MRI a rave


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 03:11 [#02624393]
Points: 20627 Status: Addict



ADHD is effectively a lack of dopamine, ironically. that
you're pinging all over because there's not enough momentum
to keep a solid course. perhaps some things going on with
serotonin as well, but that's off somewhere else


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 03:41 [#02624394]
Points: 20627 Status: Addict



that it would make sense if schizophrenia is a
too-much-dopamine problem. i think i've even read that
somewhere. essentially, instead of being infinitely
tangential like me, you'd pick a single tangent and go way.
too. deep. there are at least a few schizophrenics here and
i'm talking about at least one of you, but i'm not saying
which, because you'd all be correct to be drawn in by
this... tangent


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 03:53 [#02624395]
Points: 20627 Status: Addict



hey cool

the stock art of the frazzled chick is brill, first off. but
it's filtered down to this questionable site that
Researchers have identified dopamine as one of the major
neurotransmitters involved in schizophrenia symptoms. Over
time, they’ve discovered that the symptoms are largely
caused by high levels of dopamine in the brain
and this
jives with what i remember reading through... better quality
saurces



that imagine you're in front of a network of doors, each of
which lead to more doors, and you have to find the wedge of
cheese (i'll go with jahrlsberg; i could really go for some
jahrlsberg right now).

that you're confronted with 16 doors. going through one
reveals another bank of 16 doors, and each of those doors
lead to another bank of 16. and find the cheese.

one strategy is to try the doors layer-by layer -- open the
first door in the opening scene; no cheese? try the second.
then all of the first sixteen. this is "breadth-first"

another strategy is to open the first door in the opening
scene, then open the first door in the second layer, the the
first door in the third, until the game runs out of memory
and there's just a brick wall. this is "depth-first"

and i think dopamine is not, really, like "the happy
chemical" so much as a modulator for breadth-first (less
dopamine) vs. depth-first (more dopamine)

but then the pruning of neural density during childhood
development is probably an underlying cause of both ADHD and
schizophrenia. i really feel they are two sides of the same
coin, though


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 03:59 [#02624396]
Points: 20627 Status: Addict



shit, that's a hell of a functional giggle. you can see me
going breadth-first, then and there: well, what kind of
cheese is it?

less than a minute after i bashed out the above, i think:
the fuck does that even matter to the point i was making?
and i've gone wide; breadth-first. stepping a door over to
details that perhaps detract from the overall point. but,
arguably, going through door #1 over and over until you hit
the end has you going like a bullet train through a bunch of
trapdoors and you're in a pit


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 05:56 [#02624398]
Points: 20627 Status: Addict



alright, based on that (could be an accident, could be me
just working to help myself) i think i can rework that to be
more succinct:

lack of dopamine, adhd, i'm using a cheese maze as a
metaphor and i get hung up on what kind of cheese it is.
long experience running my brain, i more or less powered
through it, and got out with just (some shit) before ruining
the flow of my point entirely. getting lost in a miasma of
details and the point drifts off.

too much dopamine, schizophrenia, you're using a cheese maze
as a metaphor and just then an ad on a bus going by reminds
you of a thought you had staring at cheese in the store
three years ago, and you're sure of it now, the whole
concept of a cheese maze is an eldritch plot -- an irony,
really -- that, by encouraging you to re-use this common
metaphor, they trap you in a plane of lower thinking. and
there are absolutely no details at all and you've shot way
past the point


 

offline Tony Danza from nuked west on 2023-01-21 12:38 [#02624400]
Points: 3128 Status: Regular



cats


 

offline mermaidman on 2023-01-21 13:57 [#02624401]
Points: 7660 Status: Regular



THEY SAY videogames, social media, internet are all dopamine
hits they ain’t no coke but still probably why people are
addicted to them we might be too


 

offline EpicMegatrax from Greatest Hits on 2023-01-21 18:43 [#02624413]
Points: 20627 Status: Addict



everyone has their limits

i'd actually quite admit to throwing out my toys out of the
crib, recently. i've quit so much online shit because...
it's shit now; it's shit. people using discord and mastodon
before those collapse in about a year and a half. then kind
of like, "you know what, i wasted too much time on this crap
anyways"

also, feedbro is really fucking buggy, after a while with
it. you click on some feed and the fucking idiot extension
is running javascript on all the stories so it starts
autoplaying media from something 16 pages down or an article
image just jams up the window so you can't read or click
anything. the fact that it's running this shit, that it
blocks noscript and adblock plus, well, double fuck it.

i recommend vivaldi, and its built-in feed reader


 

offline steve mcqueen from caerdydd (United Kingdom) on 2023-01-28 21:16 [#02624712]
Points: 5798 Status: Regular



i luvs it
also get some Mg pills down yr neck


 

offline steve mcqueen from caerdydd (United Kingdom) on 2023-01-28 21:25 [#02624713]
Points: 5798 Status: Regular



"on the same wavelength" - fascinating expression
first heard it in junior school when they stuck me with
all the chess players


 


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